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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.31%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,310 are advancing while 2,807 are declining, suggesting a mixed market tone.

Dow Jones
51,285.73
Change
-237.33-0.46%
S&P 500
7,376.86
Change
+23.13+0.31%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,310
24H Losers
2,807

52 Week Gainers

#Stock52 Week Range
4401NeOnc Technologies Holdings, Inc.NTHI$3.39+4.06%117.42K$88.90M$2.50 - $12.000.00%
4402Lexeo Therapeutics, Inc.LXEO$2.90+2.84%611.03K$237.52M$2.55 - $10.990.00%
4403X-Energy, Inc.XE$10.03+11.67%3.95M$3.16B$8.68 - $37.100.00%
4404Intrusion Inc NewINTZ$0.59-3.08%130.82K$14.48M$0.47 - $1.800.00%
4405Dyadic International, Inc.DYAI$0.34-1.18%62.22K$13.46M$0.33 - $1.600.00%
4406Cardiff Oncology, Inc.CRDF$0.77+1.63%229.28K$59.98M$0.75 - $3.310.00%
4407Sound Point Meridian Capital, Inc.SPMC$5.61+0.91%8.20K$114.99M$5.43 - $16.750.00%
4408XCEL BRANDS INC.XELB$0.37+0.55%17.77K$2.54M$0.27 - $2.470.00%
4409AeroVironment, Inc.AVAV$111.59+8.84%947.54K$5.67B$100.53 - $408.250.00%
4410ABVC BioPharma, Inc.ABVC$0.96+0.42%10.31K$25.73M$0.71 - $3.060.00%
4411Stewards, Inc.SWRD$2.38-16.96%217.15K$501.48M$1.46 - $7.500.00%
4412Solarmax Technology Inc.SMXT$3.88+2.51%1.33K$18.42M$1.82 - $15.240.00%
4413Hydrofarm Holdings Group, Inc.HYFM$0.73+1.83%42.33K$3.53M$0.50 - $3.200.00%
4414Greenwave Technology Solutions, Inc.GWAV$2.08+5.33%3.37K$6.19M$1.91 - $8.500.00%
4415StubHub Holdings, Inc.STUB$6.12-2.95%3.26M$2.32B$5.21 - $19.870.00%
4416Blink Charging CoBLNK$0.51+24.75%6.69M$73.34M$0.38 - $1.700.00%
4417Cytosorbents Corp.CTSO$4.72-0.87%3.25K$14.89M$2.84 - $17.000.00%
4418ARS Pharmaceuticals, Inc.SPRY$2.73+3.58%2.32M$270.99M$2.46 - $13.150.00%
4419BeyondSpring Inc.BYSI$0.64+1.03%28.26K$26.23M$0.42 - $2.440.00%
4420Rigetti Computing, Inc.RGTI$11.41+15.58%13.18M$3.81B$9.19 - $37.140.00%
4421HomesToLife LtdHTLM$1.08-5.36%2.55K$97.31M$1.00 - $4.190.00%
4422Masonglory LimitedMSGY$4.06+14.90%360.64K$7.40M$1.73 - $52.800.00%
4423Rezolve AI PLCRZLV$1.27+4.10%3.59M$428.82M$1.16 - $4.970.00%
4424NexMetals Mining Corp.NEXM$1.25+3.33%41.64K$44.75M$1.20 - $4.710.00%
4425AEye, Inc.LIDR$0.77-13.16%1.13M$35.84M$0.77 - $3.050.00%
4426ZoomInfo Technologies Inc.GTM$3.54-0.29%3.77M$1.03B$2.54 - $11.230.00%
4427Nano Labs LtdNA$1.37-3.12%30.11K$28.19M$1.35 - $5.160.00%
4428BTC Digital Ltd.BTCT$0.66+0.03%99.12K$11.15M$0.43 - $2.750.00%
4429Oxford Lane Capital Corp.OXLC$4.95+1.22%1.74M$484.76M$4.62 - $15.390.00%
4430The Generation Essentials GroupTGE$0.38+9.25%96.02K$23.70M$0.33 - $1.900.00%
4431Century Casinos Inc.CNTY$0.56-2.59%22.41K$15.90M$0.45 - $2.280.00%
4432Evommune, Inc.EVMN$6.59+2.20%191.54K$215.58M$4.94 - $33.200.00%
4433Humacyte, Inc.HUMA$0.43+6.98%3.42M$118.62M$0.34 - $1.520.00%
4434Gloo Holdings, Inc.GLOO$2.63-3.33%194.54K$265.44M$2.60 - $9.980.00%
4435eXoZymes Inc.EXOZ$4.53+0.49%8.76K$42.15M$3.24 - $18.400.00%
4436Metagenomi Therapeutics, Inc.MGX$0.72-4.21%297.71K$27.09M$0.62 - $2.280.00%
4437DataMeds AI, Inc.MEDS$1.15-4.10%90.42K$5.19M$0.82 - $12.310.00%
4438Natural Health Trends Corp.NHTC$0.81-11.66%125.28K$6.86M$0.75 - $4.000.57%
4439Tigo Energy, Inc.TYGO$0.73+1.69%259.46K$55.41M$0.70 - $5.330.00%
4440Verde Clean Fuels, Inc.VGAS$1.02+4.59%6.33K$22.60M$0.92 - $3.350.00%
4441Azio AI Holdings, Inc.AZIO$0.60-10.41%442.19K$10.29M$0.57 - $2.060.00%
4442BellRing Brands, Inc.BRBR$9.21-6.27%1.22M$1.07B$7.33 - $33.560.00%
4443Blend Labs, Inc.BLND$0.95-17.08%2.05M$220.89M$0.86 - $3.440.00%
4444C1 Fund Inc.CFND$2.21-3.06%60.36K$15.86M$2.04 - $7.100.00%
4445Ready Capital CorporationRC$0.94-12.40%1.83M$155.94M$0.92 - $3.050.28%
4446Niagen Bioscience, Inc.NAGE$2.08-1.43%299.32K$165.26M$2.04 - $7.550.00%
4447Net Lease Office PropertiesNLOP$9.23+2.11%97.47K$136.67M$8.80 - $30.262.50%
4448Empery Digital Inc.EMPD$2.00-2.90%102.31K$56.43M$1.95 - $6.630.00%
4449Nouveau Monde Graphite Inc.NMG$0.82+1.24%1.28M$269.58M$0.80 - $3.590.00%
4450Skillsoft Corp.SKIL$3.56-1.38%28.01K$32.44M$3.43 - $13.040.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
NeOnc Technologies Holdings, Inc. (NTHI) currently leads with a 52-week gain of 65.54% as of 2026-11-06 23:22 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.