Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.25%⁩, the S&P 500 is ⁦+0.34%⁩, and the Nasdaq Composite is ⁦+0.86%⁩. Across individual stocks, 2,064 are advancing while 3,053 are declining, suggesting a mixed market tone.

Dow Jones
51,394.48
Change
-128.58-0.25%
S&P 500
7,378.54
Change
+24.81+0.34%
Nasdaq Composite
24,523.625
Change
+208.628+0.86%
24H Gainers
2,064
24H Losers
3,053

52 Week Losers

#Stock52 Week Range
5001Polyrizon Ltd.PLRZ$11.34-2.16%1.58K$27.70M$2.88 - $18.200.00%
5002Opus Genetics, Inc.IRD$4.19+5.49%337.58K$346.29M$1.70 - $7.070.00%
5003Funko, Inc.FNKO$6.24+1.71%1.17M$348.44M$2.72 - $7.350.00%
5004BrightSpring Health Services, Inc.BTSG$67.38+2.44%1.12M$13.41B$30.64 - $73.750.00%
5005Eagle Bancorp Inc.EGBN$33.76+0.06%97.15K$1.03B$15.58 - $35.050.01%
5006Axogen, Inc.AXGN$49.70+2.06%401.86K$2.97B$23.00 - $52.910.00%
5007MBX Biosciences, Inc.MBX$51.32+6.15%206.49K$2.47B$21.90 - $72.640.00%
5008Flexsteel IndustriesFLXS$71.82-2.09%16.42K$298.91M$34.50 - $90.640.01%
5009Ovid Therapeutics Inc.OVID$2.77+8.33%2.29M$540.19M$1.18 - $3.100.00%
5010HireQuest, Inc.HQI$17.54+4.59%6.48K$243.81M$7.38 - $20.840.01%
5011Acadian Asset Management Inc.AAMI$91.57-0.65%241.71K$3.25B$41.47 - $98.520.00%
5012Satellogic Inc.SATL$3.40+16.61%2.89M$486.16M$1.25 - $12.000.00%
5013Cogent Biosciences, Inc.COGT$31.07+4.77%611.40K$5.39B$13.93 - $43.730.00%
5014Turn Therapeutics Inc.TTRX$8.99+0.45%45.92K$288.80M$2.57 - $16.450.00%
5015Cracker Barrel Old Country Store, Inc,.CBRL$65.92-3.05%292.77K$1.47B$24.85 - $73.670.01%
5016Pyxis Tankers Inc.PXS$5.67-1.97%32.60K$58.11M$2.62 - $8.340.00%
5017Definium Therapeutics, Inc.DFTX$32.83+7.35%583.77K$4.41B$14.62 - $49.700.00%
5018JFrog Ltd.FROG$100.90+34.68%4.63M$12.44B$34.05 - $105.760.00%
5019Pershing Square Inc.PS$51.75+1.17%295.90K$18.66B$22.01 - $60.400.00%
5020Ironwood Pharmaceuticals, Inc. -IRWD$4.39+9.06%2.33M$725.90M$1.88 - $5.780.00%
5021Kymera Therapeutics, Inc.KYMR$130.84+2.09%352.70K$11.17B$56.75 - $138.000.00%
5022Marex Group LimitedMRX$69.05+5.79%363.07K$4.92B$30.30 - $79.110.00%
5023Globus Maritime LimitedGLBS$2.56+1.19%61.40K$55.36M$1.14 - $4.060.00%
5024Roma Green Finance LimitedROMA$6.13-11.08%1.92K$364.83M$1.16 - $11.770.00%
5025Nexa Resources S.ANEXA$11.51+1.77%439.23K$1.52B$5.05 - $16.890.00%
5026Abercrombie & Fitch Co.ANF$152.21-2.70%404.28K$6.46B$65.45 - $172.000.00%
5027Alto Neuroscience Inc.ANRO$24.18+9.10%361.75K$949.07M$10.62 - $37.480.00%
5028Personalis, Inc.PSNL$15.71+1.09%2.14M$1.64B$4.96 - $18.890.00%
5029Palvella Therapeutics, Inc.PVLA$172.04+10.67%311.17K$2.20B$72.22 - $176.410.00%
5030Dell Technologies Inc.DELL$329.83+4.02%6.22M$104.04B$110.22 - $595.510.01%
5031Lumentum Holdings Inc.LITE$529.98+4.31%3.69M$48.01B$215.35 - $1,143.000.00%
5032Aehr Test SystemsAEHR$52.64+7.69%2.13M$1.72B$18.70 - $147.400.00%
5033LifeStance Health Group, Inc.LFST$13.95+4.13%2.15M$5.33B$5.10 - $15.660.00%
5034MARRIOTT VACATIONS WORLDWIDE CORPORATIONVAC$110.50+3.37%117.28K$3.80B$44.58 - $131.340.03%
5035Hyperliquid Strategies Inc.PURR$8.75+0.34%7.01M$2.01B$3.01 - $14.760.00%
5036Westrock Coffee CompanyWEST$8.83-13.50%436.29K$862.05M$3.59 - $11.000.00%
5037Concentra Group Holdings Parent, Inc.CON$42.17+0.47%712.29K$5.38B$18.55 - $44.340.01%
5038MarineMax, Inc.HZO$52.73-0.02%443.93K$1.16B$21.42 - $52.890.00%
5039Hongli Group Inc.HLP$3.64+9.20%339.80K$272.27M$0.34 - $4.690.00%
5040TOP Financial Group LimitedTOP$12.53+5.92%86.09K$1.35B$3.06 - $17.420.00%
5041Park-Ohio Holdings Corp.PKOH$43.62+8.75%71.29K$632.05M$18.06 - $53.300.01%
5042Ultralife CorporationULBI$15.64+0.13%41.47K$260.70M$4.90 - $15.790.00%
5043CeriBell, Inc.CBLL$26.54+2.54%178.55K$1.02B$11.27 - $28.890.00%
5044CryoPort, Inc.CYRX$19.14+19.88%1.56M$969.42M$7.61 - $19.530.00%
5045Cheesecake Factory (The)CAKE$107.91-2.69%491.04K$5.37B$43.07 - $118.630.01%
5046Amylyx Pharmaceuticals, Inc.AMLX$28.68+4.24%563.51K$3.20B$10.83 - $41.140.00%
5047Aura Minerals Inc.AUGO$76.52+7.66%339.66K$6.41B$32.77 - $110.320.00%
5048Commercial Vehicle Group, Inc.CVGI$3.19-1.83%133.98K$129.82M$1.29 - $5.880.00%
5049Dianthus Therapeutics, Inc.DNTH$85.41+3.74%350.00K$4.68B$33.85 - $117.880.00%
5050Hamilton Beach Brands Holding CompanyHBB$32.73+1.45%47.03K$322.66M$13.75 - $39.990.01%

Anthropic (PRE): Win NVIDIA H200

Claim PRE points for guaranteed prizes up to $3K

Anthropic (PRE): Win NVIDIA H200

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Polyrizon Ltd. (PLRZ) currently shows a 52-week decline of 106.31% as of 2026-11-06 18:52 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.