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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.32%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,304 are advancing while 2,813 are declining, suggesting a mixed market tone.

Dow Jones
51,286.21
Change
-236.85-0.46%
S&P 500
7,376.92
Change
+23.19+0.32%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,304
24H Losers
2,813

52 Week Gainers

#Stock52 Week Range
4551Gaxos.ai Inc.GXAI$0.39+9.84%173.62K$4.34M$0.34 - $2.630.00%
4552Fangdd Network Group LtdDUO$0.53-2.47%13.34K$20.27M$0.42 - $2.440.00%
4553Soligenix, Inc.SNGX$0.34-0.87%106.76K$7.29M$0.28 - $1.700.00%
4554Stratum Holdings Corp.SRTM$0.17-4.00%352.36K$233.11K$0.15 - $0.680.00%
4555Dermata Therapeutics, Inc.DRMA$0.77+1.72%60.01K$3.82M$0.60 - $4.660.00%
4556Ambitions Enterprise Management Co. L.L.CAHMA$1.110.00%17.18K$32.14M$0.76 - $39.500.00%
4557Heron Therapeutics, Inc.HRTX$0.29+2.54%1.11M$54.30M$0.26 - $1.570.00%
4558Locafy LimitedLCFY$1.04+0.38%13.38K$2.34M$0.97 - $6.200.00%
4559Cheche Group Inc.CCG$8.60+1.06%12.09K$16.98M$4.11 - $36.050.00%
4560ITG, Inc.ITG$4.57+8.16%594.40K$274.20M$4.12 - $19.260.00%
4561Creative Global Technology Holdings LimitedCGTL$2.40+4.13%2.08K$4.64M$2.27 - $96.000.00%
4562Borealis Foods Inc.BRLS$0.94-15.32%37.22K$20.18M$0.60 - $3.870.00%
4563AETHLON MEDICAL INC.AEMD$5.46+2.05%6.13K$3.89M$1.41 - $25.660.00%
4564MicroAlgo, Inc.MLGO$2.26-3.48%31.57K$27.90M$2.20 - $9.110.00%
4565Intelligent Bio Solutions Inc.INBS$1.99+9.94%73.47K$6.60M$1.35 - $24.900.00%
4566Zenta Group Company LimitedZTG$0.47+0.17%64.86K$13.33M$0.45 - $12.250.00%
4567Datacentrex, Inc.DTCX$1.03+2.50%100.12K$48.79M$0.93 - $4.980.00%
4568Primech Holdings Ltd.PMEC$0.31+14.80%7.49K$11.83M$0.25 - $1.370.00%
4569Heartbeam, Inc.BEAT$0.41+2.58%809.44K$22.82M$0.35 - $4.000.00%
4570Capstone Energy Plus, Inc.CEPL$2.95+14.04%630.95K$96.53M$2.26 - $12.330.00%
4571Intensity Therapeutics, Inc.INTS$3.00-0.37%15.37K$9.79M$2.80 - $15.000.00%
4572Fervo Energy CompanyFRVO$9.03+16.11%8.15M$2.75B$7.63 - $42.650.00%
4573Eastern International Ltd.ELOG$0.64-13.51%10.72K$8.15M$0.40 - $2.830.00%
4574Quantum Biopharma LtdQNTM$2.12+2.37%40.50K$8.08M$2.02 - $12.420.00%
4575Dogwood Therapeutics, Inc.DWTX$1.28+20.19%163.23K$43.48M$0.90 - $7.040.00%
4576enCore Energy Corp.EU$0.63-0.24%3.47M$122.92M$0.62 - $3.670.00%
4577Golden Heaven Group Holdings LtdGDHG$0.99-8.18%325.13K$58.83M$0.98 - $5.200.00%
4578Tvardi Therapeutics, Inc.TVRD$0.96+11.67%54.33K$12.81M$0.77 - $5.690.00%
4579Tenax Therapeutics, Inc.TENX$1.69+3.37%621.18K$63.06M$1.31 - $19.400.00%
4580NET Power Inc.NPWR$0.81+5.76%248.45K$71.58M$0.76 - $3.630.00%
4581Bit Digital, Inc.BTBT$0.73+3.77%26.06M$264.34M$0.69 - $3.310.00%
4582Tilray Brands, Inc.TLRY$2.92+3.91%4.25M$432.28M$2.48 - $15.700.00%
4583Processa Pharmaceuticals, Inc.PCSA$1.91-1.70%8.33K$5.34M$1.04 - $8.880.00%
4584Rani Therapeutics Holdings, Inc.RANI$0.55+4.96%450.52K$62.91M$0.51 - $2.630.00%
4585Anbio BiotechnologyNNNN$3.93+7.24%31.96K$157.35M$3.09 - $44.730.00%
4586PowerCompute, Inc.PWCM$0.53+9.58%148.13K$1.34M$0.43 - $2.550.00%
4587Richtech Robotics Inc.RR$0.89+6.94%3.43M$164.80M$0.80 - $5.600.00%
4588Rocket One Inc.RKTO$0.41+0.75%121.69K$10.08M$0.38 - $2.450.00%
4589Iveda Solutions, Inc.IVDA$0.20+7.01%84.85K$2.53M$0.18 - $1.520.00%
4590APOLLO COMMERCIAL REAL ESTATE FINANCE, INC.ARI$2.32-3.64%22.20M$298.35M$2.27 - $11.240.47%
4591Ainos, Inc.AIMD$0.69+9.93%61.90K$5.10M$0.56 - $3.880.00%
4592EVOGENE LTD.EVGN$0.27-21.12%402.59K$4.89M$0.26 - $1.280.00%
4593Enveric Biosciences, Inc.ENVB$1.43-0.36%10.26K$6.38M$1.17 - $13.250.00%
4594loanDepot, Inc.LDI$0.63+1.44%1.63M$144.82M$0.48 - $3.240.00%
4595Rail Vision Ltd.RVSN$2.75+6.49%19.64K$6.04M$2.60 - $13.540.00%
4596One and One Green Technologies. Inc.YDDL$1.02+1.98%15.18K$58.27M$0.96 - $16.230.00%
4597Teads Holding CoTEAD$0.19+6.13%290.94K$18.34M$0.15 - $1.420.00%
4598Rapid Micro Biosystems, Inc.RPID$0.65+2.31%141.41K$29.45M$0.60 - $4.940.00%
4599Longeveron Inc.LGVN$1.81+4.68%38.68K$5.50M$1.31 - $12.300.00%
4600Full House Resorts, Inc.FLL$0.61-16.18%968.62K$22.23M$0.59 - $3.370.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Gaxos.ai Inc. (GXAI) currently leads with a 52-week gain of 73.80% as of 2026-11-06 22:48 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.