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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.46%⁩, the S&P 500 is ⁦+0.32%⁩, and the Nasdaq Composite is ⁦+1.09%⁩. Across individual stocks, 2,306 are advancing while 2,811 are declining, suggesting a mixed market tone.

Dow Jones
51,286.21
Change
-236.85-0.46%
S&P 500
7,376.92
Change
+23.19+0.32%
Nasdaq Composite
24,579.425
Change
+264.428+1.09%
24H Gainers
2,306
24H Losers
2,811

52 Week Gainers

#Stock52 Week Range
4651aTyr Pharma, Inc.ATYR$6.39+6.80%61.30K$16.57M$4.07 - $44.400.00%
4652Terrestrial Energy Inc.IMSR$2.83+10.72%1.49M$302.97M$2.44 - $15.490.00%
4653Incannex Healthcare LimitedIXHL$2.24-1.98%103.28K$28.13M$2.17 - $14.910.00%
4654Health In Tech, Inc.HIT$0.57+2.88%10.01K$30.61M$0.49 - $3.050.00%
4655Alset Inc.AEI$0.49-1.40%21.36K$19.18M$0.49 - $3.980.00%
4656Armlogi Holding Corp.BTOC$1.81-2.94%14.64K$5.16M$1.80 - $11.490.00%
4657BioHarvest Sciences Inc.BHST$1.58+6.71%55.72K$25.95M$1.37 - $9.250.00%
4658Bakkt, Inc.BKKT$4.30+2.76%953.65K$68.45M$3.86 - $25.000.00%
4659Maris-Tech Ltd.MTEK$0.28-5.10%109.42K$2.67M$0.21 - $2.820.00%
4660Avax One Technology LtdAVX$4.42+4.51%63.06K$32.66M$2.81 - $31.800.00%
4661NeuroOne Medical Technologies CorporationNMTC$0.86-1.82%26.86K$7.87M$0.77 - $6.120.00%
4662AI Financial CorporationAIFC$0.17+7.10%1.52M$24.05M$0.16 - $1.080.00%
4663PTIX$0.000.00%0$0$0.13 - $2.380.00%
4664Guardforce AI Co., LimitedGFAI$0.17-1.96%141.04K$5.43M$0.17 - $0.980.00%
4665Reliance Global Group, Inc.EZRA$2.15-4.48%3.57K$3.62M$1.75 - $17.200.13%
4666Akebia Therapeutics, Inc.AKBA$0.40-5.64%11.62M$111.12M$0.37 - $2.110.00%
4667DirectBooking Technology Co., LtdZDAI$1.35+5.06%3.54K$11.16M$1.10 - $12.000.00%
4668Vivid Seats Inc.SEAT$2.07-26.28%297.99K$23.29M$2.03 - $11.060.00%
4669Neumora Therapeutics, Inc.NMRA$0.51+1.77%588.74K$94.89M$0.32 - $3.650.00%
4670Nakamoto Inc.NAKA$5.68+1.44%91.57K$104.21M$3.33 - $32.610.00%
4671DarioHealth Corp.DRIO$2.35-10.46%13.75K$23.08M$2.35 - $14.770.00%
4672American Vanguard CorporationAVD$0.96+1.55%211.97K$28.35M$0.92 - $5.550.00%
4673BOXABL, Inc.BXBL$1.91+0.52%75.60K$502.43M$1.80 - $11.990.00%
4674CervoMed Inc.CRVO$1.41-2.76%583.39K$21.36M$1.30 - $10.000.00%
4675SunCar Technology Group Inc.SDA$0.38+146.94%539.71M$22.53M$0.13 - $2.450.00%
4676Upexi, Inc.UPXI$0.64-2.85%1.11M$56.26M$0.54 - $3.650.00%
4677FTC Solar, Inc.FTCI$1.55+21.88%2.07M$28.39M$1.17 - $12.750.00%
4678MacKenzie Realty Capital, Inc.MKZR$0.94-2.03%11.77K$2.59M$0.83 - $5.220.00%
4679Psyence Biomedical LtdPBM$3.00-0.50%24.31K$11.46M$1.92 - $18.620.00%
4680Yueda Digital HoldingYDKG$0.97-6.98%31.11K$5.53M$0.73 - $5.400.00%
4681Haoxin Holdings LimitedHXHX$0.14+2.84%509.67K$1.44M$0.12 - $1.470.00%
4682Australian Oilseeds Holdings LimitedCOOT$0.27-1.81%3.53K$7.56M$0.26 - $1.530.00%
4683Aqua Metals, Inc.AQMS$1.25+18.80%41.14K$4.47M$1.02 - $8.390.00%
4684Compass Therapeutics, Inc.CMPX$0.76+10.41%1.62M$136.33M$0.67 - $6.880.00%
4685Niki BioSolutions, Inc.NIKI$1.67+12.50%9.06K$1.43M$1.39 - $12.240.00%
4686Corteva, Inc.CTVA$11.90-1.16%8.56M$7.94B$11.24 - $90.970.06%
4687MBody AI Ltd.MBAI$2.45+2.51%4.08K$37.47M$1.61 - $27.440.00%
4688Freightos LimitedCRGO$0.68+13.44%43.84K$34.78M$0.58 - $4.240.00%
4689PN Smart Energy LimitedPN$2.38+1.05%39.23K$34.38M$1.77 - $40.000.00%
4690York Space Systems Inc.YSS$6.26+13.61%1.92M$836.51M$5.26 - $44.540.00%
4691Polestar Automotive Holding UK PLCPSNY$4.25+4.42%112.89K$693.47M$3.22 - $24.400.00%
4692CISO Global, Inc.CISO$0.18+9.51%405.07K$8.11M$0.15 - $1.040.00%
4693RenX Enterprises Corp.RENX$0.93+4.98%19.26K$3.23M$0.79 - $7.000.00%
4694Greenland Energy CompanyGLND$2.38+11.45%1.07M$121.13M$1.09 - $23.000.00%
4695The OLB Group, Inc.OLB$0.18+4.38%350.12K$5.68M$0.16 - $1.800.00%
4696Lucid Group, Inc.LCID$3.29+10.23%9.40M$1.29B$2.37 - $18.100.00%
4697Ucommune International LtdUK$1.55+5.42%15.17K$1.04M$1.31 - $10.500.00%
4698DNA X, Inc.SONM$2.10-11.30%45.41K$3.13M$2.02 - $11.900.00%
4699Cerenome, Inc.CNSY$0.64-4.06%506.18K$4.86M$0.61 - $4.250.00%
4700Amesite Inc.AMST$0.53-2.12%24.33K$3.45M$0.52 - $3.150.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
aTyr Pharma, Inc. (ATYR) currently leads with a 52-week gain of 79.27% as of 2026-11-06 22:11 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.